1 Result for "

ND2110

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ND2110" in MCE Product Catalog:

Cat. No.: HY-117622
CAS No.: 1388894-17-4
Target:  

IRAK

Research Areas:  

Inflammation/Immunology Cancer

ND-2110 is a selective IRAK4 inhibitor (Ki: 7.5 nM). ND-2110 binds to the ATP pocket of IRAK4. ND-2110 targets the subset of activated B cell-like (ABC) subtype of diffuse large B cell lymphoma (DLBCL) cell lines with MYD88 L265P mutations,. ND-2110 inhibits LPS-induced TNF production, alleviates collagen-induced arthritis, and blocks gout formation in mouse models .
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