1 Result for "

NDNA-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NDNA-3" in MCE Product Catalog:

Cat. No.: HY-149432
Target:  

HSP Potassium Channel

Research Areas:  

Cancer

NDNA3 (compound 14) is a selective inhibitor of Hsp90α (IC50: 0.51 μM). NDNA3 is a permanently charged analog with low membrane permeability and low toxicity to Ovcar-8 (IC50: 12.66 μM) and MCF-10A (IC50: 11.72 μM) cells. NDNA3 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90α-dependent client proteins .
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