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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
NU227326
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "NU227326" in MCE Product Catalog:
Cat. No.: HY-173066
CAS No.: 3048196-52-4
Research Areas:
NU227326 is a blood-brain barrier penetrant IDO1 PROTAC degrader, with a DC50 of 4.5 nM in HiBiT degradation assays. NU227326 degrades IDO1 in U87 and GBM43 cells, with DC50 values of 7.1 nM and 11.8 nM, respectively (WB assays). NU227326 is applicable to research related to glioblastoma, prostate cancer, triple-negative breast cancer, pancreatic cancer, and ovarian cancer .
Cat. No.: HY-173067
CAS No.: 3048196-74-0
Research Areas:
IDO1 ligand-1 is the target protein ligand of PROTAC NU227326 (HY-173066). NU227326 can be used to degrade IDO1 .
Cat. No.: HY-173068
Target:
Research Areas:
2-(4-(Piperazin-1-yl)piperidin-1-yl)acetic acid is the linker that can be used for synthesis of PROTAC degrader NU227326 (HY-173066) .
Cat. No.: HY-173069
Research Areas:
E3 Ligase Ligand-linker Conjugate 169 is the conjugate composed of an E3 ligase ligand for Cereblon and a linker that can be used for synthesis of PROTAC degrader NU227326 (HY-173066) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
