1 Result for "

NZ66

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NZ66" in MCE Product Catalog:

Cat. No.: HY-158408
CAS No.: 3062992-25-7
Target:  

ULK Mitophagy TSPO

Research Areas:  

Neurological Disease

NZ-66 is a ULK1-Recruiting Chimera (ULKREC) and heterobifunctional chimeric molecule composed of a BL-918-derived ULK1 agonist linked to a mitochondrial outer membrane-targeting TSPO ligand via a six-carbon hexane linker. NZ-66 is a mitophagy inducer recruits ULK1 to mitochondria to induce ULK1-dependent mitophagy, enhanced by mitochondrial insult, independently of the PRKN/PINK axis. NZ-66 can be used for the research of parkinson’s disease .
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