1 Result for "

ODE-Bn-PMEG

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ODE-Bn-PMEG" in MCE Product Catalog:

Cat. No.: HY-156584
CAS No.: 1626364-18-8
Target:  

Endogenous Metabolite

Research Areas:  

Infection

ODE-Bn-PMEG is an antiviral compound with strong inhibitory activity against HPV-11, -16, and -18. ODE-Bn-PMEG effectively reduced transient amplification of viral DNA in transfected cells at concentrations well below its cytotoxic levels. ODE-Bn-PMEG showed increased uptake in human foreskin fibroblasts and was able to be efficiently converted to the active antiviral metabolite PMEG diphosphate in vitro. The P-chiral enantiomer of ODE-Bn-PMEG showed comparable antiviral activity, indicating its potential application against multiple HPV types. ODE-Bn-PMEG is a promising candidate for local inhibition of HPV-16, HPV-18, and other high-risk types .
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