8 Results for "

PAPR

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "PAPR" in MCE Product Catalog:

PARPYnD
PARPYnD
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Cat. No.: HY-145749
CAS No.: 2561483-27-8
Target:  

PARP

Domaines de recherche:  

Cancer

PARPYnD is a PARP enzyme photoaffinity probe (AfBP) based on the triple PARP1/2/6 inhibitor AZ9482 (HY-119653), which induces breast cancer Formation of multipolar spindles (MPS) in cells. PARPYnD inhibits PAPR wih IC50 of 38 nM (PARP1), 6 nM (PARP2), 230 nM (PARP6), respectively. PARPYnD enriches recombinant PARP6 incorporated into cell lysates and inhibits PARP6 in cell-free assays, but it does not label PARP6 in intact cells .
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
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Cat. No.: HY-W141392
CAS No.: 2245842-16-2
Target:  

Nucleoside Antimetabolite/Analog Xanthine Oxidase Phosphoramidites

Domaines de recherche:  

Cancer

2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
6-O-Methylinosine
6-O-Methylinosine
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Cat. No.: HY-152696
CAS No.: 5746-29-2
Target:  

Xanthine Oxidase Nucleoside Antimetabolite/Analog

Domaines de recherche:  

Others

6-O-Methylinosine is a hypoxanthine analogue. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite
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Cat. No.: HY-W392836
CAS No.: 128219-85-2
Target:  

Nucleoside Antimetabolite/Analog Xanthine Oxidase Phosphoramidites

Domaines de recherche:  

Cancer

2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
2-Chloro-6-methoxypurine riboside
2-Chloro-6-methoxypurine riboside
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Cat. No.: HY-W039271
CAS No.: 15465-92-6
Synonyms: 2-Chloro-6-O-methyl-inosine
Target:  

Nucleoside Antimetabolite/Analog Xanthine Oxidase

Domaines de recherche:  

Cancer

2-Chloro-6-methoxypurine riboside is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
2′-C-Methyl-6-O-methylinosine
2′-C-Methyl-6-O-methylinosine
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Cat. No.: HY-154017
CAS No.: 565450-78-4
Target:  

Nucleoside Antimetabolite/Analog Xanthine Oxidase

Domaines de recherche:  

Cancer

2′-C-Methyl-6-O-methylinosine is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
2-Chloro-2'-deoxy-6-O-methylinosine
2-Chloro-2'-deoxy-6-O-methylinosine
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Cat. No.: HY-154393
CAS No.: 146196-07-8
Target:  

Nucleoside Antimetabolite/Analog Xanthine Oxidase

Domaines de recherche:  

Cancer

2-Chloro-2'-deoxy-6-O-methylinosine is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
6-Methoxypurine-9-β-D-5’(R)-C-methylriboside
6-Methoxypurine-9-β-D-5’(R)-C-methylriboside
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Cat. No.: HY-152678
Target:  

Nucleoside Antimetabolite/Analog Xanthine Oxidase

Domaines de recherche:  

Cancer

6-Methoxypurine-9-β-D-5’(R)-C-methylriboside is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
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