1 Result for "

PF03715455

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PF03715455" in MCE Product Catalog:

Cat. No.: HY-18862
CAS No.: 1056164-52-3
Target:  

p38 MAPK

Research Areas:  

Inflammation/Immunology

PF-03715455 is a potent inhaled p38 MAPK inhibitor. PF-03715455 shows some selectivity for p38α over p38β with respective IC50 values of 0.88 and 23 nM. PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 has potential for the treatment of COPD (chronic obstructive pulmonary disease) .
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