1 Result for "

PF06747143

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PF06747143" in MCE Product Catalog:

Cat. No.: HY-P992439

Target:  

CXCR

Research Areas:  

Cancer

PF-06747143 is recombinant anti-human antibody targeting CXCR4. PF-06747143 blocks CXCL12-induced calcium flux, F-actin polymerization, chemotaxis, cell migration, and leukemic cell bone marrow homing. PF-06747143 reduces tumor burden and improves survival in mouse models of hematologic malignancies. PF-06747143 can be used for the research of chronic lymphocytic leukemia, acute myeloid leukemia, and hematologic malignancies .
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