1 Result for "

PYD106

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PYD106" in MCE Product Catalog:

Cat. No.: HY-117734
CAS No.: 1560894-05-4
Purity:  98.13%
Target:  

iGluR

Research Areas:  

Neurological Disease

PYD-106 is a stereoselective pyrrolidinone (PYD) positive allosteric modulator for GluN2C-containing NMDA receptors. PYD-106 increases opening frequency and open time of single channel currents activated by maximally effective concentrations of agonist but only has modest effects on glutamate and glycine EC50. PYD-106 selectively enhances the responses of diheteromeric GluN1/GluN2C receptors but not triheteromeric GluN1/GluN2A/GluN2C receptors .
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