1 Result for "

Peluntamig

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Peluntamig" in MCE Product Catalog:

Cat. No.: HY-P991016
CAS No.: 2928515-21-1
Synonyms: PT-217

Target:  

CD47

Research Areas:  

Inflammation/Immunology

Peluntamig (PT-217) is a bispecific antibody targeting DLL3 and CD47. The antibody arms of Peluntamig specifically bind to DLL3 on small cell lung cancer tumor cells while blocking the CD47-SIRPa interaction, thereby effectively stimulating macrophage phagocytosis and inducing NK cell-mediated cytotoxicity. Peluntamig exhibits significant anti-tumor activity against small cell lung cancer and also has favorable safety profiles. Peluntamig can be used in a variety of tumor-related studies including those on small cell lung cancer and L1210 leukemia .
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