1 Result for "

Ponsegromab

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Ponsegromab" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99241
CAS No.: 2368950-15-4
Synonyms: PF 06946860

Research Areas:  

Cancer

Ponsegromab is a Growth differentiation factor 15 (GDF15) inhibitor with human, cynomolgus monkey, and mouse target IC50 values of 0.123 nM, 0.053 nM, and 0.102 nM, respectively . Ponsegromab acts as a chemosensitizer, increases intracellular reactive oxygen species, reduces glutathione levels . Ponsegromab can be used for the research of oxaliplatin-resistant colorectal cancer .
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