1 Result for "

Prexasertib-d4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Prexasertib-d4" in MCE Product Catalog:

Cat. No.: HY-18174S
Synonyms: LY2606368-d4
Prexasertib-d4 (LY2606368-d4) is the deuterium labeled Prexasertib (HY-18174). Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. Prexasertib inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib shows potent anti-tumor activity .
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