1 Result for "

RIPK1-IN-33

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RIPK1-IN-33" in MCE Product Catalog:

Cat. No.: HY-175027
Target:  

RIP kinase Ferroptosis

Research Areas:  

Neurological Disease

RIPK1-IN-33 is a blood-brain barrier-permeable and orally active RIPK1 inhibitor, with an IC50 of 0.115 μM. RIPK1-IN-33 demonstrates remarkable anti-ferroptosis activity, radical scavenging capacity (IC50 = 123.3 μM), and anti-lipid peroxidation effects (IC50 = 9.72 μM). RIPK1-IN-33 markedly reduces cerebral infarction volume and improves neurological function scores in transient middle cerebral artery occlusion (tMCAO) model. RIPK1-IN-33 can be used for the study of ischemic stroke .
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