1 Result for "

RO5323441

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RO5323441" in MCE Product Catalog:

Cat. No.: HY-P991430
Synonyms: TB-403

Target:  

VEGFR

Research Areas:  

Cancer

RO5323441 (TB-403) is a human IgG1 monoclonal antibody (mAb) targeting PlGF. RO5323441 inhibits the binding of human PlGF-1 or PlGF-2 to VEGFR-1 (IC50 values are 0.1 and 0.2 nM, respectively). RO5323441 blocks PlGF-induced VEGFR-1 phosphorylation in Flt-1-transfected HEK293 cells. RO5323441 has antitumor activity .
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