8 Results for "

SIAH1

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "SIAH1" in MCE Product Catalog:

3
BI-3802
BI-3802
0 Images
3 Cited Publications
Art. -Nr.: HY-108705
CAS. Nr.: 2166387-65-9
Reinheit:  99.27%
Target:  

Molecular Glues Bcl-2 Family

Forschungsgebiete:  

Cancer

BI-3802, a chemical probe, is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity [1] .
SIAH1 Human Pre-designed siRNA Set A
SIAH1 Human Pre-designed siRNA Set A
Art. -Nr.: HY-RS12891
Target:  

Small Interfering RNA (siRNA)

Forschungsgebiete:  

Others

SIAH1 Human Pre-designed siRNA Set A contains three designed siRNAs for SIAH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Siah1 Rat Pre-designed siRNA Set A
Siah1 Rat Pre-designed siRNA Set A
Art. -Nr.: HY-RS29319
Target:  

Small Interfering RNA (siRNA)

Forschungsgebiete:  

Others

Siah1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Siah1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
BG-DBCO
BG-DBCO
0 Images
Art. -Nr.: HY-W1124386
CAS. Nr.: 1820756-74-8
Synonyms: SNAP-DBCO
BG-DBCO is a DBCO-conjugated Benzylguanine. BG-DBCO, SNAP-E3 fusion protein and Ligand-N3 form a protein complex. BG-DBCO is conjugated with JQ1-N3-C10 to obtain BG-JQ1. BG-JQ1, administered together with SIAH1-SN mRNA, effectively inhibits the growth of small cell carcinoma of the adrenocortical gland [1].
SIAH1 Antibody (YA6878)
SIAH1 Antibody (YA6878)
0 Images
Art. -Nr.: HY-P87190
Synonyms: E3 ubiquitin-protein ligase SIAH1 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

SIAH1 Antibody (YA6955)
SIAH1 Antibody (YA6955)
0 Images
Art. -Nr.: HY-P87272
Synonyms: E3 ubiquitin-protein ligase SIAH1 antibody; FLJ08065 antibody; hSIAH1 antibody; HUMSIAH antibody; Seven in absentia homolog 1 (Drosophila) antibody; Seven in absentia homolog 1 antibody; SIAH 1 antibody; SIAH 1a antibody; SIAH E3 ubiquitin protein ligase 1 antibody; SIAH-1 antibody

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

BC-DXI-495
BC-DXI-495
0 Images
Art. -Nr.: HY-182399
CAS. Nr.: 2421117-94-2
Target:  

Aminoacyl-tRNA Synthetase

Forschungsgebiete:  

Cancer

BC-DXI-495 is a AIMP2-DX2 inhibitor. BC-DXI-495 disrupts the interaction of HSP70 and destabilizes DX2. BC-DXI-495 induces DX2 degradation via Siah1-mediated ubiquitination. BC-DXI-495 exerts tumor suppressive activity in cancer cells. BC-DXI-495 serves as a chemical probe to elucidate the mechanism of action of arylsulfonamide-based DX2 inhibitors. BC-DXI-495 can be used in lung cancer research [1].
BI-3802 (Standard)
BI-3802 (Standard)
0 Images
Art. -Nr.: HY-108705R
CAS. Nr.: 2166387-65-9
Target:  

Molecular Glues Reference Standards Bcl-2 Family

Forschungsgebiete:  

Cancer

BI-3802 (Standard) is the analytical standard of BI-3802 (HY-108705). This product is intended for research and analytical applications. BI-3802, a chemical probe, is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity [1] .
Assay Types