1 Result for "

SIJ1777

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SIJ1777" in MCE Product Catalog:

Cat. No.: HY-164400
CAS No.: 839707-55-0
Target:  

MEK ERK Akt Apoptosis

Research Areas:  

Cancer

SIJ1777 is a GNF-7 (HY-10943) derivative, possesses potent anti-cancer effects on melanoma cells harboring BRAF class I/II/III mutations. SIJ1777 substantially inhibits the activation of MEK, ERK, and AKT. SIJ1777 remarkably induces apoptosis and significantly blocks migration, invasion, and anchorage-independent growth of melanoma cells harboring BRAF class I/II/II mutations .
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