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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
SJ44236
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "SJ44236" in MCE Product Catalog:
Cat. No.: HY-170900
Research Areas:
SJ44236 is a BET PROTAC degrader with activity against BRD2, BRD3 and BRD4 (DC50 = 127 pM). SJ44236 induces ubiquitination and proteasomal degradation by forming a ternary complex with BET proteins and CRBN-DDB1. SJ44236 downregulates c-Myc, upregulates p53 and reduces cancer cell viability. SJ44236 can be used for the research of leukemia and medulloblastoma .
Cat. No.: HY-W890189
CAS No.: 2413038-90-9
Target:
Research Areas:
E3 ligase Ligand 54 is the ligand for E3 ligase Cereblon and can be used for synthesis of PROTAC Degrader SJ44236 (HY-170900) .
Cat. No.: HY-170901
CAS No.: 2789679-85-0
Research Areas:
E3 Ligase Ligand-linker Conjugate 165 is a conjugate of an E3 ligase ligand and a linker, which can be used for the synthesis of PROTAC SJ44236 (HY-170900) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
