14 Results for "

SMART

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "SMART" in MCE Product Catalog:

1
GE11
GE11
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1 Cited Publications
Cat. No.: HY-P10128
CAS No.: 875142-25-9
Target:  

Biochemical Assay Reagents

Research Areas:  

Inflammation/Immunology

GE11 is a active peptide and combines with colloidal drug delivery systems as smart carriers for antitumor drugs and can be used for cancer study .
Polyacrylamide,Anion,Mw 18 million
Polyacrylamide,Anion,Mw 18 million
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Cat. No.: HY-W115727B
CAS No.: 9003-05-8
Synonyms: PAM,Anion,Mw 18 million
Polyacrylamide,Anion,Mw 18 million (PAM,Anion,Mw 18 million) is a multifunctional high molecular weight anionic polyacrylamide copolymer. The anionic properties of Polyacrylamide,Anion,Mw 18 million enable it to be used as a flocculant to achieve charge neutralization and aggregation, while its high molecular weight properties provide viscoelastic properties for fluid applications. Polyacrylamide series materials can maintain enzyme activity in enzyme immobilization, act as drug carriers to achieve controlled release, serve as smart materials responding to temperature/pH stimuli, and be used for in vitro toxin adsorption and soft tissue filling through mechanisms such as physical entrapment, covalent binding or chemical crosslinking. Polyacrylamide finds applications in biomedical engineering, environmental management and industrial applications .
Polyacrylamide,average Mn 150000
Polyacrylamide,average Mn 150000
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Cat. No.: HY-W115727E
CAS No.: 9003-05-8
Synonyms: PAM,average Mn 150000
Polyacrylamide, average Mn 150000 (PAM, average Mn 150000) is a versatile, high-molecular-weight polyacrylamide copolymer. Polyacrylamide series materials can maintain enzyme activity in enzyme immobilization, act as drug carriers to achieve controlled release, serve as smart materials responding to temperature/pH stimuli, and be used for in vitro toxin adsorption and soft tissue filling through mechanisms such as physical entrapment, covalent binding or chemical crosslinking. Polyacrylamide finds applications in biomedical engineering, environmental management and industrial applications .
Polyacrylamide,Anion,Mw 14-16 million
Polyacrylamide,Anion,Mw 14-16 million
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Cat. No.: HY-W115727A
CAS No.: 9003-05-8
Synonyms: PAM,Anion,Mw 14-16 million
Polyacrylamide, Anion, Mw 14-16 million is a multifunctional high molecular weight anionic polyacrylamide copolymer. The anionic properties of Polyacrylamide, Anion, Mw 14-16 million enable it to be used as a flocculant to achieve charge neutralization and aggregation, while its high molecular weight properties provide viscoelastic properties for fluid applications. Polyacrylamide series materials can maintain enzyme activity in enzyme immobilization, achieve controlled release as a drug carrier, respond to temperature/pH stimulation as a smart material, and can also be used for in vitro toxin adsorption and soft tissue filling through mechanisms such as physical embedding, covalent bonding or chemical cross-linking. Polyacrylamide can be used in biomedical engineering, environmental management and industrial applications .
SMART1
SMART1
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Cat. No.: HY-W998345
Target:  

PROTACs PDK-1 Akt

Research Areas:  

Cancer

SMART1 is a highly specific and CRBN-dependent PROTAC that can effectively degrade Smurf1. SMART1 can block the PDK1-Akt signaling pathway in KRAS mutant colorectal cancer. SMART1 can inhibit tumor growth in KRAS mutant colorectal cancer (CRC) xenograft models .
Polyacrylamide,average Mn 40000
Polyacrylamide,average Mn 40000
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Cat. No.: HY-W115727D
CAS No.: 9003-05-8
Synonyms: PAM,average Mn 40000
Polyacrylamide (PAM), average Mn 40000 is a versatile, high-molecular-weight polyacrylamide copolymer. Polyacrylamide series materials can maintain enzyme activity in enzyme immobilization, act as drug carriers to achieve controlled release, serve as smart materials responding to temperature/pH stimuli, and be used for in vitro toxin adsorption and soft tissue filling through mechanisms such as physical entrapment, covalent binding or chemical crosslinking. Polyacrylamide finds applications in biomedical engineering, environmental management and industrial applications .
Polyacrylamide,Nonionic,Mw 5-6 million
Polyacrylamide,Nonionic,Mw 5-6 million
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Cat. No.: HY-W115727C
CAS No.: 9003-05-8
Synonyms: Acrylamide polymer,Nonionic,Mw 5-6 million
Polyacrylamide (Acrylamide polymer),Nonionic,Mw 5-6 million is a multifunctional, high-molecular-weight nonionic polyacrylamide copolymer. Polyacrylamide-based materials can maintain enzyme activity in enzyme immobilization, act as drug carriers for controlled release, function as smart materials responsive to temperature/pH stimuli, and be applied in in vitro toxin adsorption and soft tissue filling, through action mechanisms such as physical entrapment, covalent binding or chemical crosslinking. Polyacrylamide finds applications in biomedical engineering, environmental management and industrial applications .
Smurf1 ligand 1
Smurf1 ligand 1
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Cat. No.: HY-169049
Target:  

Ligands for Target Protein for PROTAC

Research Areas:  

Cancer

Smurf1 ligand 1 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). Smurf1 ligand 1 can be used for synthesis SMART1 (HY-W998345) .
2-Hydroxypropyl acrylate
2-Hydroxypropyl acrylate
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Cat. No.: HY-W017050
CAS No.: 999-61-1
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

2-Hydroxypropyl acrylate (HPA) is a severe irritant and corrosive to the skin. 2-Hydroxypropyl acrylate (HPA) is extensively applied in fibre, adhesives, rubber industry, paints and coatings industry .
SMARt751
SMARt751
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Cat. No.: HY-171317
CAS No.: 1616370-52-5
Target:  

Bacterial

Research Areas:  

Infection Neurological Disease

SMARt751 targets the transcriptional regulatory factor VirS, inhibits its DNA binding ability, upregulates the mymA operon expression, thereby activating Ethionamide (HY-B0276), enhancing the antimicrobial activity of Ethionamide. SMARt751 enhances the antibacterial activity of Ethionamide against M. tuberculosis, reverses the Ethionamide resistance. SMARt751 improves the antibacterial effect of Ethionamide and reduces its effective dose in mouse models .
Thalidomide-piperidine
Thalidomide-piperidine
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Cat. No.: HY-169050
CAS No.: 2924858-38-6
Target:  

E3 Ligase Ligand-Linker Conjugates

Research Areas:  

Cancer

Thalidomide-piperidine is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-piperidine can be used to synthesize SMART1 (HY-W998345) .
Ara-SH
Ara-SH
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Cat. No.: HY-154971
Target:  

Apoptosis

Research Areas:  

Cancer

Ara-SH is a Cytarabine mercaptopropionic acid-substituted derivative. Ara-SH is used as the trigger to fabricate a smart Cytarabine and Venetoclax-coloaded nanoparticle (AV-NP) through self-assembly. Ara-SH exhibits remarkable synergistic antileukemia effects in vitro and in vivo .
DCDAPH
DCDAPH
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Cat. No.: HY-D1684
CAS No.: 125113-96-4
DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid (Aβ) plaques (λex/λem=597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates (Ki=37 nM, Kd=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo .
Reactive oxygen responsive hydrogel
Reactive oxygen responsive hydrogel
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Cat. No.: HY-184600
Target:  

Biochemical Assay Reagents Metal Nanoparticles

Reactive oxygen species responsive hydrogels are a novel class of smart hydrogels, formed by the cross-linking of ROS-responsive modules through covalent, coordination, or supramolecular interactions. Due to the introduction of these ROS-responsive modules, these hydrogels exhibit a sensitive response to the oxidative stress microenvironment present in organisms. PVA-TSPBA hydrogel is a hydrogel formed by the cross-linking polymerization of polyvinyl alcohol (PVA) and the reactive oxygen species-sensitive cross-linking agent N1-(4-benzyl borate)-N3-(4-phenyl borate)N1,N1,N3,N3-tetramethyl-1,3-propanediamine (TSPBA). This hydrogel consists of two parts: a boric acid precursor (TSPBA) and an aqueous solution of PVA. The boric acid bonds on TSPBA and the hydroxyl groups on PVA rapidly cross-link to form borate ester bonds, thus forming the hydrogel.
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