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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
SRSF10
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "SRSF10" in MCE Product Catalog:
Referencia número: HY-RS13791
Target:
Áreas de investigación:
SRSF10 Human Pre-designed siRNA Set A contains three designed siRNAs for SRSF10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS19818
Target:
Áreas de investigación:
Srsf10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srsf10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS26314
Target:
Áreas de investigación:
Srsf10 Rat Pre-designed siRNA Set A contains three designed siRNAs for Srsf10 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-183831
No. CAS: 3034312-19-8
GPS167 is a CLK kinase inhibitor that potently and selectively inhibits recombinant human CLK1, CLK2 and CLK4. By inhibiting CLK-mediated phosphorylation of SRSF10, GPS167 upregulates the protein-binding ability of CLK1 and CLK4 with SRSF10, downregulates oncogenic BCLAF1-L and upregulates tumor-suppressive BCLAF1-S, regulates alternative splicing of genes such as MDM2 and MDM4, stabilizes p53 protein and induces DNA damage, ultimately triggering tumor cell apoptosis. GPS167 can block the epithelial-mesenchymal transition process of tumors, activate intracellular double-stranded RNA-mediated antiviral immune responses, and produce synergistic cytotoxicity when combined with microtubule-targeting drugs. GPS167 can be used in research related to various cancers including colorectal cancer .
Referencia número: HY-RS25982
Target:
Áreas de investigación:
Tra2b Rat Pre-designed siRNA Set A contains three designed siRNAs for Tra2b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
