1 Result for "

STAMBP-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "STAMBP-IN-1" in MCE Product Catalog:

Cat. No.: HY-141852
CAS No.: 896683-78-6
Purity:  98.37%
Target:  

Deubiquitinase

Research Areas:  

Inflammation/Immunology

STAMBP-IN-1 is a small-molecule inhibitor of STAMBP deubiquitinase, and interrupts STAMBP-Ub-NALP7 interaction. STAMBP-IN-1 decreases protein level of its inflammasome substrate NALP7 and suppresses IL-1b release after Toll-like receptor (TLR) agonism. STAMBP-IN-1 inhibits the activity of STAMBP to cleave recombinant di-Ub with an IC50 value of 0.33 mM [1].
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