1 Result for "

SYR127063

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SYR127063" in MCE Product Catalog:

Cat. No.: HY-111250
CAS No.: 871026-18-5
Target:  

EGFR

Research Areas:  

Cancer

SYR127063 is a potent and selective human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitor with an IC50 of 11 nM. SYR127063 binds to the active site of the HER2 kinase domain in an ATP-competitive manner, thereby preventing the formation of the conserved salt bridge required for kinase activation. SYR127063 can be used in research related to breast cancer, ovarian cancer and gastric cancer .
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