1 Result for "

THR-β agonist 12

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "THR-β agonist 12" in MCE Product Catalog:

Cat. No.: HY-184939
CAS No.: 3063509-17-8
THR-β agonist 12 is an orally active, potent, and highly selective thyroid hormone receptor β (THR-β) agonist (EC50 = 36 nM). THR-β agonist 12 shows no significant activity against THRα and exhibits no cardiotoxicity in vivo. THR-β agonist 12 inhibits lipid synthesis by activating the AMPK-ACC-SREBP1 signaling axis. THR-β agonist 12 can be used on research into metabolic dysfunction-associated steatohepatitis (MASH) and related metabolic diseases .
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