1 Result for "

TMC114-d9

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TMC114-d9" in MCE Product Catalog:

Cat. No.: HY-112585
CAS No.: 1133378-37-6
Synonyms: TMC114-d9; UIC-94017-d9
Target:  

HIV HIV Protease

Research Areas:  

Infection Inflammation/Immunology

Darunavir-d9 (TMC114-d9) is the deuterium labeled Darunavir. Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 μM; IC90 = 0.009 μM) with minimal cytotoxicity .
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