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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
TRIB
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "TRIB" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P74491
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TRIBbles homolog 3; TRB-3; SINK; C20orf97; NIPK; SKIP3
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Cat. No.: HY-168274
CAS No.: 3100306-42-8
PROTAC TRIB2 degrader-1 (Compound 5k) is an effective TRIB2 degrader that selectively induces TRIB2 degradation through the CRBN-dependent ubiquitin-proteasome pathway. PROTAC TRIB2 degrader-1 can inhibit cell proliferation and induce cell apoptosis, and can be used in cancer research .
Cat. No.: HY-RS15017
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TRIB3 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIB3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16261
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Trib3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trib3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15015
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TRIB1 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11964
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RIBC2 Human Pre-designed siRNA Set A contains three designed siRNAs for RIBC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21732
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Ribc2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ribc2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-168276
CAS No.: 3036972-61-6
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Boc-Nonanol is a PROTAC linker. Boc-Nonanol can be used in the synthesis of PROTAC TRIB2 degrader-1 (HY-168274) .
Cat. No.: HY-168277
CAS No.: 3053782-32-1
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5-Aminothalidomide-C9-Boc is a E3 ligase ligand-linker conjugate, used for the synthesis of PROTAC TRIB2 degrader-1 (HY-168274) .
Cat. No.: HY-168275
CAS No.: 2652012-89-8
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TRIB2 ligand-1 is a ligand of TRIB2 (Ligands for Target Protein for PROTACs). TRIB2 ligand-1 can be used for synthesis PROTAC TRIB2 degrader-1 (HY-168274) .
Cat. No.: HY-RS15016
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TRIB2 Human Pre-designed siRNA Set A contains three designed siRNAs for TRIB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19489
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Trib2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trib2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22878
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Trib1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trib1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23486
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Trib3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trib3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25983
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Trib2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trib2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29392
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Trib1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trib1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P74492
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TRIBbles homolog 2; TRB-2; TRIB2; TRB2
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Cat. No.: HY-184178A
HF-125 is an orally active, highly selective small-molecule inhibitor of Tribbles 2 (TRIB2). HF-125 promotes the destabilization and degradation of TRIB2 protein via the proteasome pathway. HF-125 downregulates neuroendocrine markers, induces cell cycle arrest and apoptosis, inhibits tumor cell colony formation and invasion, and reverses tumor cell resistance to Enzalutamide (HY-70002). HF-125 significantly inhibits tumor growth in SCID mouse xenograft models, and exerts synergistic inhibitory effects when combined with Enzalutamide. HF-125 can be used in research related to prostate cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
