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Referencia número: HY-168277

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5-Aminothalidomide-C9-Boc

5-Aminothalidomide-C9-Boc is a E3 ligase ligand-linker conjugate, used for the synthesis of PROTAC TRIB2 degrader-1 (HY-168274) .

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No. CAS: 3053782-32-1
Fòrmula: C₂₇H₃₇N₃O₆
Peso molecular:499.60

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

5-Aminothalidomide-C9-Boc Chemical Structure

No. CAS: 3053782-32-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

5-Aminothalidomide-C9-Boc is a E3 ligase ligand-linker conjugate, used for the synthesis of PROTAC TRIB2 degrader-1 (HY-168274) ^[1].

Ver todos los productos específicos de isoformas E3 Ligase Ligand-Linker Conjugates :

Chemical Information

No. CAS 3053782-32-1
Peso molecular 499.60
Fòrmula C₂₇H₃₇N₃O₆
SMILES

O=C(OC(C)(C)C)CCCCCCCCCNC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2=O)=O)C=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Wen C, et al. Discovery of the first selective and potent PROTAC degrader for the pseudokinase TRIB2. Eur J Med Chem. 2025 Jan 5;281:117016. [Content Brief]

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

5-Aminothalidomide-C9-Boc

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5-Aminothalidomide-C9-Boc

Ver todos los productos específicos de isoformas E3 Ligase Ligand-Linker Conjugates

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

5-Aminothalidomide-C9-Boc Related Classifications

HY-168277 Related Classifications