3100306-42-8
3100306-42-8
Chemical Structure
PROTAC TRIB2 degrader-1
- CAS No.: 3100306-42-8
- Formula:C45H45FN8O6
- Molecular Weight:812.89
InChIKey: QRVWXAOLLAQJGU-UHFFFAOYSA-N
SMILES: O=C(C1=NNC2=C1C=C(C3=CC=CN=C3F)C=C2)NC4=CC5=C(C=C4)CCN(C(CCCCCCCCCNC6=CC7=C(C(N(C(CC8)C(NC8=O)=O)C7=O)=O)C=C6)=O)C5
Biological Activity: PROTAC TRIB2 degrader-1 (Compound 5k) is an effective TRIB2 degrader that selectively induces TRIB2 degradation through the CRBN-dependent ubiquitin-proteasome pathway. PROTAC TRIB2 degrader-1 can inhibit cell proliferation and induce cell apoptosis, and can be used in cancer research[1].
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PROTAC TRIB2 degrader-1 | PROTAC TRIB2 degrader-1 (Compound 5k) is an effective TRIB2 degrader that selectively induces TRIB2 degradation through the CRBN-dependent ubiquitin-proteasome pathway. PROTAC TRIB2 degrader-1 can inhibit cell proliferation and induce cell apoptosis, and can be used in cancer research. | |||||||||||||||||||||
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References
Keywords
