1 Result for "

UK370106

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "UK370106" in MCE Product Catalog:

Cat. No.: HY-107639
CAS No.: 230961-21-4
Purity:  96.70%
Target:  

MMP

Research Areas:  

Inflammation/Immunology

UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and MMP-8. UK-370106 potently inhibits cleavage of [ 3H]-fibronectin by MMP-3 (IC50 of 320 nM) and has little effect on keratinocyte migration in vitro .
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