1 Result for "

VU0424465

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VU0424465" in MCE Product Catalog:

Cat. No.: HY-114978
CAS No.: 1428630-85-6
Purity:  99.84%
Target:  

mGluR PERK

Research Areas:  

Neurological Disease

VU0424465 is a potent and partial PAM (positive allosteric modulator)-agonist for mGlu5 mediated iCa 2+ mobilization. VU0424465 exhibits high affinity at MPEP allosteric binding site, with a Ki value of 11.8 nM. VU0424465 is also a agonist for pERK1/2 in cortical neurons .
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