1 Result for "

VU6007477

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VU6007477" in MCE Product Catalog:

Cat. No.: HY-123934
CAS No.: 2220141-46-6
Target:  

P-glycoprotein

Research Areas:  

Neurological Disease

VU6007477 is a brain-penetrant, selective M1 positive allosteric modulator (PAM) with an EC50 value of 230 nM. VU6007477 is also a human P-glycoprotein (P-gp) substrate with moderate permeability. VU6007477 displays improved central nervous system (CNS) penetration over the hydroxylated congeners. VU6007477 a pyranyl amide derivative, which is promising for research of robust cholinergic seizure activity .
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