1 Result for "

VU6019650

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VU6019650" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-148502
CAS No.: 2926782-31-0
Purity:  98.61%
Target:  

mAChR

Research Areas:  

Neurological Disease

VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopaminergic reward circuitry. VU6019650 blocks Oxotremorine M iodide (HY-101372A) induced increases of neuronal firing rates of midbrain dopamine neurons in the ventral tegmental area (VTA) .
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