1 Result for "

Val70Ub pocket

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Val70Ub pocket" in MCE Product Catalog:

Cat. No.: HY-182894
Target:  

Virus Protease SARS-CoV

Research Areas:  

Infection

MR1-114 is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC50 of 0.037 μM. As a broad-spectrum inhibitor, MR1-114 maintains submicromolar activity against SARS-CoV-2 Delta, Omicron B.1.1.529 and Omicron BA.5 variants, with EC50 values of 0.18 μM, 0.39 μM and 0.20 μM, respectively. MR1-114 can be used for the research of coronavirus disease 2019 (SARS-CoV-2 infection) .
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