1 Result for "

YM1240

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YM1240" in MCE Product Catalog:

Cat. No.: HY-184270
Research Areas:  

Cancer

YM1240 is an orally active dual EZH2/HDAC inhibitor with human EZH2 IC50 0.342 μM and human HDAC IC50 0.12 μM. YM1240 inhibits EZH2 pathway to reduce H3K27me3 levels, inhibits HDAC pathway to increase H3K9ac and H4ac levels. YM1240 suppresses proliferation, induces apoptosis, induces cell cycle arrest in lymphoma cells. YM1240 exhibits antitumor efficacy in lymphoma xenograft models. YM1240 can be used for the research of lymphoma .
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