1 Result for "

YM344031

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YM344031" in MCE Product Catalog:

Cat. No.: HY-160998
CAS No.: 671204-98-1
Target:  

CCR

Research Areas:  

Inflammation/Immunology

YM-344031 is an orally active antagonist for CCR3. YM-344031 inhibits binding of Eotaxin-1 and RANTES to CCR3, with IC50 of 3.0 and 16.3 nM. YM-344031 inhibits ligand-induced rise in intracellular Ca [2+] and the ligand-induced chemotaxis. YM-344031 inhibits eotaxin-1-induced changes in eosinophil morphology in macaques blood, and prevents allergic skin reactions in a mouse allergy model .
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