1 Result for "

YQ 128

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YQ 128" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-130252
CAS No.: 2454246-18-3
Purity:  99.83%
YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC50 of 0.30 μM. YQ128 significantly and selectively suppresses the production of IL-1β, but not TNF-α, and it can cross the BBB to reach the CNS. YQ128 has anti-inflammatory activity . YQ128 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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