1 Result for "

YUM-70

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YUM-70" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-138364
CAS No.: 423145-35-1
Purity:  98.01%
Target:  

HSP Apoptosis

Research Areas:  

Cancer

YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. YUM70 also has in vivo efficacy in a pancreatic cancer xenograft model .
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