1 Result for "

ZLY06

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ZLY06" in MCE Product Catalog:

Cat. No.: HY-168049
CAS No.: 2834727-04-5
Target:  

PPAR Akt

Research Areas:  

Metabolic Disease

ZLY06 is an orally active dual agonist of peroxisome proliferator-activated receptor (PPAR) δ and γ (PPAR δ: EC50=341 nM; PPAR γ: EC50=237 nM). ZLY06 induces hepatic lipid accumulation by inhibiting the phosphorylation of AKT1, mediating the upregulation of CD36. In addition, ZLY06 significantly improves glucose and lipid metabolism without increasing body weight, and alleviates fatty liver by promoting β-oxidation of fatty acids and inhibiting hepatic lipogenesis .
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