3 Results for "

amrubicin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "amrubicin" in MCE Product Catalog:

Cat. No.: HY-B0067
CAS No.: 110267-81-7
Synonyms: SM-5887
Target:  

Topoisomerase Bacterial

연구분야:  

Cancer

Amrubicin (SM-5887) is a DNA topoisomerase II inhibitor, used for the research of cancer.
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Cat. No.: HY-B0067A
CAS No.: 110311-30-3
Synonyms: SM-5887 hydrochloride
Target:  

Topoisomerase Bacterial

연구분야:  

Cancer

Amrubicin (SM-5887) hydrochloride is a DNA topoisomerase II inhibitor, used for the research of cancer.
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Cat. No.: HY-B0067B
CAS No.: 92395-36-3
Synonyms: (R)-SM-5887
Target:  

Topoisomerase

연구분야:  

Cancer

(R)-Amrubicin ((R)-SM-5887) is an anthracycline that effectively treats lung cancer by intercalating into DNA and inhibiting topoisomerase II activity, which consequently hampers DNA replication as well as RNA and protein synthesis, leading to cell growth inhibition and apoptosis. This compound exhibits superior anti-tumor efficacy compared to traditional anthracycline drugs while lacking the cumulative cardiac toxicity typically associated with this drug class.
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