4 Results for "

cytb

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "cytb" in MCE Product Catalog:

ELQ-453
ELQ-453
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Cat. No.: HY-174342
Target:  

Cytochrome P450 Parasite

Domaines de recherche:  

Infection

ELQ-453 is an inhibitor targeting the Qo site of the Plasmodium falciparum cytochrome bc1 complex (CytB) with an IC50 value of 0.57 nM. ELQ-453 blocks the mitochondrial function of the parasite, and suppresses Plasmodium infection in mosquitoes. ELQ-453 is promising for research of malaria .
MT-CYB Human Pre-designed siRNA Set A
MT-CYB Human Pre-designed siRNA Set A
Cat. No.: HY-RS08761
Target:  

Small Interfering RNA (siRNA)

Domaines de recherche:  

Others

MT-CYB Human Pre-designed siRNA Set A contains three designed siRNAs for MT-CYB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

DNP-INT
DNP-INT
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Cat. No.: HY-119984
CAS No.: 69311-70-2
Target:  

Cytochrome P450

Domaines de recherche:  

Others

DNP-INT is a potent photosynthetic electron transport chain (PETC) inhibitor. DNP-INT competently inhibits the oxidation of plastid quinoline by binding to the Q0 site of Cyt-b6f (Kd=1.4 nM), thereby inhibiting electron transfer in plants .
ATP Synthesis-IN-4
ATP Synthesis-IN-4
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Cat. No.: HY-181602
Target:  

ATP Synthase COX Oxidative Phosphorylation AMPK

Domaines de recherche:  

Cancer

ATP Synthesis-IN-4 is a mitochondria-targeted small-molecule ligand that inhibits ATP synthesis. ATP Synthesis-IN-4 binds to mtDNA G4s in melanoma cells, thereby inducing changes in mitochondrial metabolism and inhibiting cell proliferation. ATP Synthesis-IN-4 suppresses the translation of key mitochondrial respiratory chain proteins (CYTB, ATP8, COX1, COX3, ND2) in melanoma cells, downregulates the expression of OXPHOS complexes, activates the phosphorylation of AMPK, and induces metabolic reprogramming to upregulate glycolysis. ATP Synthesis-IN-4 is applicable to relevant research on melanoma .
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