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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
isoquinolinone
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "isoquinolinone" in MCE Product Catalog:
Cat. No.: HY-W002014
CAS No.: 491-30-5
Cat. No.: HY-W000494
CAS No.: 1532-84-9
Synonyms: 1-Aminoisoquinoline
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Research Areas:
SID7970631, as an isoquinolinone analog, is a potent and selective submicromolar SF-1 inhibitor (IC50=255 nM). SID7970631 can be used for the research of cancer .
Cat. No.: HY-163512
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Anti-inflammatory agent 79 (compound 17q) is an isoquinolinone derivative-based HIF-1 inhibitor (IC50: 0.55 μM), which can effectively block HIF-1 signals and increase HIF- Degradation of 1α. Anti-inflammatory agent 79 inhibits synovial invasion and migration and inhibits angiogenesis. Anti-inflammatory agent 79 also effectively reduced foot swelling and arthritis in a mouse inflammation model, and down-regulated the levels of inflammatory factors and blood vessel proliferation in the body .
Cat. No.: HY-123569
CAS No.: 405165-77-7
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ISQ-1 hydrochloride is an isoquinolinone (IKur) blocker with potential atrial arrhythmic activity. ISQ-1 exhibits cardiac electrophysiological characteristics similar to another structurally distinct IKur blocker previously reported from our laboratory .
Cat. No.: HY-402601
Desethyl-SID 7969543 is an isoquinolinone analog of SID 7969543 (HY-107404) and a selective SF-1 (NR5A1) inhibitor. Desethyl-SID 7969543 shows no activity against RORA, VP16 and LRH-1, and exhibits no cytotoxicity at concentrations close to its SF-1 IC50 value .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
