3 Results for "

lgG2

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "lgG2" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99019
CAS No.: 1655501-53-3
Synonyms: TEV-48125; LBR-101; PF-04427429; RN-307
Fremanezumab (TEV-48125) is a humanized lgG2 monoclonal antibody that selectively and potently binds to calcitonin gene related peptide (CGRp) (IC50 values = 7.943 nM). Fremanezumab binds to mouse CGRP with an IC50 value of 19.6 nM. Fremanezumab counteracts anti-inflammatory effects of CGRP in vitro, including CGRP-mediated inhibition of LPS (HY-D1056)-induced microglial activation. Fremanezumab selectively inhibits the activation of Aδ meningeal nociceptors by cortical spreading depression (CSD) in rats. Fremanezumab can be used for the study of inflammation and chronic migraine [2] .
loading...
    loading...
Cat. No.: HY-P99552
CAS No.: 2225109-03-3
Synonyms: IBI-306

Target:  

PCSK9

Research Areas:  

Cardiovascular Disease

Tafolecimab (IBI-306) is a human lgG2 monoclonal antibody that specifically binds PCSK-9 and reduces LDL-C levels by inhibiting PCSK-9-mediated endocytosis of the LDL receptor, which in turn enhances clearance of LDL-C and leads to a reduction in LDL-C levels. Tafolecimab may be used in studies of hypercholesterolaemia .
loading...
    loading...
Cat. No.: HY-P99986

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Mouse lgG2a (D265A) kappa, Isotype Control, a mouse monoclonal antibody, is an isotype control for mouse lgG2a (D265A) antibody.
loading...
    loading...