1 Result for "

nNOS-IN-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "nNOS-IN-6" in MCE Product Catalog:

Cat. No.: HY-181711
Target:  

NO Synthase

Research Areas:  

Neurological Disease Cancer

nNOS-IN-6 is a human neuronal nitric oxide synthase (hnNOS) inhibitor with a human hnNOS Ki of 16 nM, ~1800-fold selectivity over human eNOS, ~2900-fold selectivity over human iNOS, and a rat nNOS Ki of 34 nM.nNOS-IN-6 exhibits high effective permeability in PAMPA-BBB assays, crosses the blood-brain barrier, and shows sustained systemic exposure, low clearance, and robust brain penetration in mouse in vivo pharmacokinetic studies.nNOS-IN-6 can be used for the research of neurodegenerative diseases, melanoma .
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