2 Results for "

pan-BTK

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "pan-BTK" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-139535
CAS No.: 1616428-23-9
Purity:  99.30%
Synonyms: CG-806
Target:  

FLT3 Btk Apoptosis

Research Areas:  

Cancer

Luxeptinib (CG-806) is an orally active, reversible, first-in-class, non-covalent and potent pan-FLT3/pan-BTK inhibitor. Luxeptinib induces cell cycle arrest, apoptosis or autophagy in acute myeloid leukemia cells .
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Cat. No.: HY-124153
CAS No.: 1433820-83-7
Target:  

Btk

GNE-431 is a potent, selective and noncovalent “pan-BTK inhibitor against C481R, T474I and T474Ms mutants. GNE-431 shows potency against wild-type BTK (IC50= 3.2 nM) and potency against C481S mutant (IC50= 2.5 nM). GNE-431 is proming for rasearch of haematological disorders and autoimmune diseases .
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