1 Result for "

synaptobrevin-syntaxin-SNAP-25 complex

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "synaptobrevin-syntaxin-SNAP-25 complex" in MCE Product Catalog:

Cat. No.: HY-182539
CAS No.: 1202877-06-2
Target:  

CGRP Receptor

Research Areas:  

Others Neurological Disease

DD04107 is a neuronal exocytosis inhibitor with a rat Syt1-C2B domain binding Kd of 2.4 μM. DD04107 interferes with synaptobrevin-syntaxin-SNAP-25 complex formation and Syt1-SNARE complex interaction to block α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons. DD04107 blocks inflammatory ion channel recruitment to nociceptor plasma membranes. DD04107 can be used for the research of chronic inflammatory pain, neuropathic pain, osteosarcoma pain, chemotherapy-induced peripheral neuropathy, diabetic neuropathy, inflammatory pain .
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