1 Result for "

turmorigenesis

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "turmorigenesis" in MCE Product Catalog:

Cat. No.: HY-133121
CAS No.: 2408842-51-1
Purity:  ≥98.0%
Target:  

Apoptosis WDR5

Research Areas:  

Cancer

WDR5-IN-1 is a potent and selective WD repeat domain 5 (WDR5) inhibitor, with a Kd of <0.02 nM. WDR5-IN-1 inhibits MLL1 histone methyltransferase (HMT) activity with an IC50 of 2.2 nM. WDR5-IN-1 diminishes MYC recruitment at WDR5-displaced genes and exhibits potent anti-proliferative effects in CHP-134 (neuroblastoma) and Ramos (Burkitt’s lymphoma) lines .
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