Hmgn2 - high mobility group nucleosomal binding domain 2 Gene

Also Known as Hmg17; HMG-17

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15331

Summary

Predicted to enable chromatin binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II and regulation of development, heterochronic. Located in nucleus. Is expressed in several structures, including central nervous system; eye; genitourinary system; heart; and lung. Used to study Axenfeld-Rieger syndrome type 1. Orthologous to human HMGN2 (high mobility group nucleosomal binding domain 2). [provided by Alliance of Genome Resources, Apr 2022]

Hmgn2 Products (1)

mRNA Protein Name
NM_016957.3 NP_058653.1 non-histone chromosomal protein HMG-17

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
23975681 MGI
acts upstream of or within regulation of development, heterochronic IGI
IGI: Inferred from genetic interaction
11133167 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21278158 MGI
Cellular Component GO Annotation Evidence References Source
located in female germ cell nucleus IDA
IDA: Inferred from direct assay
11133167 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

non-histone chromosomal protein HMG-17

  • high mobility group nucleosome-binding domain-containing protein 2

  • high mobility group protein 17

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06244 HMGN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20955 Hmgn2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27472 Hmgn2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hmgn2 NCBI NCBI:3151