1. GPCR/G Protein
  2. GNRH Receptor
  3. Buserelin Acetate

Buserelin Acetate 

Cat. No.: HY-13581A Purity: 99.75%
Handling Instructions

Buserelin Acetate is a gonadotropin-releasing hormone agonist (GnRH agonist).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Buserelin Acetate Chemical Structure

Buserelin Acetate Chemical Structure

CAS No. : 68630-75-1

Size Price Stock Quantity
2 mg USD 60 In-stock
Estimated Time of Arrival: December 31
5 mg USD 120 In-stock
Estimated Time of Arrival: December 31
10 mg USD 168 In-stock
Estimated Time of Arrival: December 31
50 mg USD 600 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1080 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

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Description

Buserelin Acetate is a gonadotropin-releasing hormone agonist (GnRH agonist). target: GnRH In vivo: Buserelin treatment reduced the number of neurons along the entire gastrointestinal tract, with increased relative numbers of CRF-immunoreactive submucosal and myenteric neurons in colon (p < 0.05 and p < 0.01, respectively).[1] Compared with controls, buserelin treatment caused loss of myenteric neurons in the ileum and colon (P<0.01), a thinner circular muscle layer in ileum (P<0.05) and longitudinal muscle layer in colon (P<0.05). Long term follow up of buserelin induced enteric neuropathy reveals reduced body weight, loss of myenteric neurons, thinning of muscle layers, and increased numbers of eosinophils and T lymphocytes in the gastrointestinal tract.[2] A marked enteric neuronal loss with modest effects on GI function is found after buserelin treatment. Increased feces fat content is suggested an early sign of dysfunction.[3]

Clinical Trial
Molecular Weight

1299.48

Formula

C₆₂H₉₀N₁₆O₁₅

CAS No.

68630-75-1

Sequence

{pGlu}-His-Trp-Ser-Tyr-{d-Ser(tBu)}-Leu-Arg-Pro-NHEt

Sequence Shortening

{pGlu}-HWSY-{d-S(tBu)}-LRP-NHEt

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (38.48 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7695 mL 3.8477 mL 7.6954 mL
5 mM 0.1539 mL 0.7695 mL 1.5391 mL
10 mM 0.0770 mL 0.3848 mL 0.7695 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.75%

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Keywords:

BuserelinGNRH ReceptorGonadotropin releasing hormone receptorGNRHRInhibitorinhibitorinhibit

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Product Name:
Buserelin Acetate
Cat. No.:
HY-13581A
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