1. Anti-infection
    Membrane Transporter/Ion Channel
  2. Bacterial
    Potassium Channel

Hexachlorophene (Synonyms: Hexachlorofen)

Cat. No.: HY-12637 Purity: 99.66%
Handling Instructions

Hexachlorophene (Hexachlorofen) is a highly effective antibacterial agent, causes lysis of protoplasts and leakage of intracellular contents in bacterial at high concentrations. Hexachlorophene (Hexachlorofen) is also a KCNQ1/KCNE1 (a voltage-gated potassium channel) activator, with an EC50 of 4.61 μM, used in the research of severe arrhythmia.

For research use only. We do not sell to patients.

Hexachlorophene Chemical Structure

Hexachlorophene Chemical Structure

CAS No. : 70-30-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
1 g USD 60 In-stock
Estimated Time of Arrival: December 31
5 g USD 168 In-stock
Estimated Time of Arrival: December 31
10 g   Get quote  
50 g   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

Description

Hexachlorophene (Hexachlorofen) is a highly effective antibacterial agent, causes lysis of protoplasts and leakage of intracellular contents in bacterial at high concentrations[1]. Hexachlorophene (Hexachlorofen) is also a KCNQ1/KCNE1 (a voltage-gated potassium channel) activator, with an EC50 of 4.61 μM, used in the research of severe arrhythmia[2].

IC50 & Target

EC50: 4.61 μM (KCNQ1/KCNE1)[2]

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (245.76 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4576 mL 12.2880 mL 24.5761 mL
5 mM 0.4915 mL 2.4576 mL 4.9152 mL
10 mM 0.2458 mL 1.2288 mL 2.4576 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.14 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.14 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.14 mM); Clear solution

Molecular Weight

406.90

Formula

C₁₃H₆Cl₆O₂

CAS No.

70-30-4

SMILES

OC1=C(Cl)C=C(Cl)C(Cl)=C1CC2=C(O)C(Cl)=CC(Cl)=C2Cl

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.66%

  • 订单必须小于1g!20181019;一般危险品,经陈委评估可上线 唐冬采购 危险化学品批量下线20180605;高博要求上线20180802;不竞价
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Product Name:
Hexachlorophene
Cat. No.:
HY-12637
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Hexachlorophene

Cat. No.: HY-12637