1. Anti-infection
    Membrane Transporter/Ion Channel
  2. Bacterial
    Potassium Channel
  3. Hexachlorophene

Hexachlorophene (Synonyms: Hexachlorofen)

Cat. No.: HY-12637 Purity: 99.66%
Handling Instructions

Hexachlorophene (Hexachlorofen) is a highly effective antibacterial agent, causes lysis of protoplasts and leakage of intracellular contents in bacterial at high concentrations. Hexachlorophene (Hexachlorofen) is also a KCNQ1/KCNE1 (a voltage-gated potassium channel) activator, with an EC50 of 4.61 μM, used in the research of severe arrhythmia.

For research use only. We do not sell to patients.

Hexachlorophene Chemical Structure

Hexachlorophene Chemical Structure

CAS No. : 70-30-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

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Description

Hexachlorophene (Hexachlorofen) is a highly effective antibacterial agent, causes lysis of protoplasts and leakage of intracellular contents in bacterial at high concentrations[1]. Hexachlorophene (Hexachlorofen) is also a KCNQ1/KCNE1 (a voltage-gated potassium channel) activator, with an EC50 of 4.61 μM, used in the research of severe arrhythmia[2].

IC50 & Target

EC50: 4.61 μM (KCNQ1/KCNE1)[2]

Clinical Trial
Molecular Weight

406.90

Formula

C₁₃H₆Cl₆O₂

CAS No.

70-30-4

SMILES

OC1=C(Cl)C=C(Cl)C(Cl)=C1CC2=C(O)C(Cl)=CC(Cl)=C2Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (245.76 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4576 mL 12.2880 mL 24.5761 mL
5 mM 0.4915 mL 2.4576 mL 4.9152 mL
10 mM 0.2458 mL 1.2288 mL 2.4576 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.14 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.14 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.14 mM); Clear solution

*All of the co-solvents are provided by MCE.

Purity: 99.66%

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2

Keywords:

HexachloropheneHexachlorofenBacterialPotassium ChannelKcsAInhibitorinhibitorinhibit

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Hexachlorophene
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