Signaling Pathway

Aromatase

Aromatase

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Aromatase Inhibitors & Modulators (5)

Product Name Catalog No. Brief Description
Aminoglutethimide

HY-B0237

Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM.

Anastrozole

HY-14274

Anastrozole(ZD1033) is a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis.

Exemestane

HY-13632

Exemestane(FCE 24304) is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.

Formestane

HY-B0697

Formestane(CGP-32349; 4-OHA) is a selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer.

Letrozole

HY-14248

Letrozole(CGS-20267) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant.