Galactokinase
Galactokinase; GALK; GAL; GALK1; GAL1
Galactokinase is a key enzyme involved in galactose metabolism, mainly responsible for phosphorylating galactose to galactose-1-phosphate. Galactokinasedysfunction leads to metabolic disorders such as the autosomal recessive genetic disease galactosemia, in which abnormal metabolized galactose and its metabolite accumulates in the body, causing probably intellectual disability, liver dysfunction and cataracts[1].
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Productos relacionados con Galactokinase (2)
Productos relacionados con (2)
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GALK1-IN-1
0 ImagesGALK1-IN-1 (Compound 4) is a galactokinase inhibitor (IC50: 4.2129 μM).
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NCGC00238624
0 ImagesReferencia número: HY-173642No. CAS: 2768230-55-1NCGC00238624 is a selective galactokinase (GALK1) inhibitor with IC50s of 7.69 μM and 13.67 μM against the human and mouse recombinant GALK1, respectively. NCGC00238624 is inactive against GALK2 and other kinases at 10 μM. NCGC00238624 can be used for the study of classic galactosemia.
