143-28-2
Chemical Structure
Oleyl alcohol
- CAS. Nr.: 143-28-2
- Formula:C18H36O
- Molecular Weight:268.48
IUPAC Name: (Z)-octadec-9-en-1-ol
InChIKey: ALSTYHKOOCGGFT-KTKRTIGZSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCCO
Biological Activity: Oleyl alcohol is an anti-tumor compound that inhibits tumor growth. Oleyl alcohol induces cytotoxicity, cell death and apoptosis. The intracellular accumulation of Oleyl alcohol correlates with its cytotoxicity against tumor cells. Oleyl alcohol forms enhancer-enriched fluid domains in stratum corneum lipids, increases the retention of diclofenac diethylamine in ex vivo human epidermis and dermis, and enhances the skin permeability of diclofenac diethylamine. Oleyl alcohol can be used in studies related to neuroblastoma[1][2][3].
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Oleyl alcohol | 98.00% | Oleyl alcohol is an anti-tumor compound that inhibits tumor growth. Oleyl alcohol induces cytotoxicity, cell death and apoptosis. The intracellular accumulation of Oleyl alcohol correlates with its cytotoxicity against tumor cells. Oleyl alcohol forms enhancer-enriched fluid domains in stratum corneum lipids, increases the retention of diclofenac diethylamine in ex vivo human epidermis and dermis, and enhances the skin permeability of diclofenac diethylamine. Oleyl alcohol can be used in studies related to neuroblastoma. | ||||||||||||||||||||
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- [1]. Orienti I, et al. Enhancement of oleyl alcohol anti tumor activity through complexation in polyvinylalcohol amphiphilic derivatives. Drug delivery. 2007 Apr;14(4):209-17. [Content Brief]
- [2]. Vallejo Orrego A,et al. Selective synthesis of oleyl alcohol via catalytic and non-catalytic liquid-phase methyl oleate reduction. J Am Oil Chem Soc. 2023;10.1002/aocs.12687
- [3]. Kováčik A, et al. Time-Dependent Differences in the Effects of Oleic Acid and Oleyl Alcohol on the Human Skin Barrier. Molecular pharmaceutics. 2023 Dec 04;20(12):6237-6245. [Content Brief]
Keywords
